Regardless of the cause, the end result is the same: impedance in the normal flow of urine from the renal pelvis into the proximal ureter, resulting in caliectasis and hydronephrosis. This may lead to progressive deterioration of renal function and, thus, often requires intervention to relieve the obstruction and restore the normal flow of urine. Defining the pertinent anatomy, the degree of obstruction, and differential renal function is key to determining whether and when intervention is necessary. Contemporary management of the obstructed ureteropelvic junction UPJ in the adult has evolved.
Current Urology Reports. This paper reviews the current literature on both the pathophysiology and treatment options for ureteropelvic junction obstruction UPJO. The pathophysiology of UPJO is still unknown but appears to be multifactorial. Perhaps future molecular studies will give us an answer to the etiology and also a pathway in preventing UPJO. Treatment options have been studied in-depth, and the gold standard is open pyeloplasty.
Skip to search form Skip to main content. Surgical management of ureteropelvic junction obstruction in adults. Kausik and Joseph W. Kausik , Joseph W. Segura Published in International braz j urol : official journal of….
A year-old man presents to his primary care physician with complaints of fatigue and lethargy over the past few months. He also notes left flank and inguinal pain, which has become progressively more symptomatic over the past few weeks. He has no prior history of kidney stones or abdominal surgery. Physical examination was remarkable only for mild left costovertebral angle tenderness.